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Nicki Norris

Nicki Norris

Symphony Clinical Research, USA

Title: Novel techniques for improving clinical trial subject retention


Nicki Norris is the CEO of Symphony Clinical Research, a provider of specialized in-home and alternate-site clinical services. She has more than 30 years of experience as a Healthcare Executive. She has spent 20 years at Baxter, lead a high growth dialysis company; a blood collection/processing organization; and a Gold-Standard Laboratory accrediting organization. She has an MBA from the UofI Urbana-Champaign, passed the CPA exam, and serves as a VP of the Chicago chapter of the HBA. She has spoken at dozens of industry conferences (DIA, Outsourcing, Innovations in Clinical Trials, Center Watch, Site Solution Summit, SCOPE, CBI Rare Disease and NORD conference on Rare Diseases).


Each year thousands of patients drop out of clinical trials for any variety of reasons. Though some dropouts are a result of uncontrollable circumstances, many others are preventable. With over 85% of trials failing to retain enough patients, it is clear, more can be done to boost subject retention. This session will outline a few of the many reasons to subject drop-outs occurring. We will identify innovative approaches for improving subject retention, and risk mitigating strategies for minimizing its impact on study validity. This session will also discuss techniques used within phase 2, phase 3 and open label extension studies to decrease the number of missed visit time-points. Lastly, this session will offer metrics demonstrating the impact of in-home and alternate site clinical services on the number of missed visits, subjects lost to follow-up and overall retention.