Biography
Biography: Dominique Guinn
Abstract
Within this literature review, this author will systematically identify and examine recent and relevant literature regarding barriers to minority participation in clinical trials. This literature review uses elements of Garrard’s Matrix Method and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The databases accessed to conduct this literature review were: (a) Medline/PubMed, (b) CINAHL, (c) Nursing- ProQuest Database, (d) Scopus, and (e) Google Scholar. Search terms included MeSH terms and Subject Headings where appropriate. The metanalysis identified barriers to participation in clinical trials by minorities. Mistrust of medical personnel because of unethical research conducted on African Americans, current and historical segregation, racism, and unjust treatment within the health care system were some of the barriers identified. Dr. Guinn is living with Acute Lymphoblastic Leukemia and a participant in clinical trials at MD Anderson Cancer Center. MD Anderson has outreach programs dedicated to promoting education and awareness around clinical trials to minorities in underserved communities. They have enlisted multiple strategies to recruit minorities using innovative approaches to break down invisible barriers and rebuild people trust in medicine. As a result of their efforts they have been able to increase minority participation in clinical trials.