Clinical Trials

Clinical Trials on different Diseases and Medical Devices

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Clinical Trials for different diseases and disorders are conducted for evaluating one or more interventions (for example, drugs, medical devices, approaches to surgery or radiation therapy) for treating a disease, syndrome, or condition and also finding ways to prevent the initial development or recurrence of a disease or condition. These can include medicines, vaccines, or lifestyle changes, among other approaches.

The lack of specificity in available AD tests has become a major burden on AD therapeutics development programs, which hold a relatively high 99.6% failure rate. Part of the problem is the 20% to 50% of clinical trial participants who are not suffering from AD, but another form of dementia, that dilute and complicate trial data across sites. The development of treatments effective in the early onset of AD also requires patients to be effectively screened for AD risk and MCI. Responding to outstanding pharmaceutical industry demand for effective AD screening, Amarantus BioScience adjusted its development plan for its AD assay to focus on investigational use only (IUO) applications initially rather than CLIA clearance. The company plans to target a $150 million opportunity in supplying tests and biomarker services to pharmaceutical clients involved in AD therapeutics development.